Activyl contains indoxacarb, an active ingredient, which was specifically developed to overcome insect resistance in crop protection. Indoxacarb is a pro-insecticidal compound that requires enzymatic activation in the flea where it is converted into its highly potent insecticidal form. Activyl is metabolized differently in insects than in mammals. Unlike insects, mammals mostly metabolize indoxacarb into nontoxic metabolites.
For external use on cats and kittens only. Do not use on kittens under 8 weeks of age. Do not use on cats weighing less than 9lb. Do not use on cats (male or female) intended for breeding, pregnant or nursing. Consult a veterinarian before using this product on debilitated, aged, or medicated cats. Accidental ingestion by the cat may cause intermittent excess salivation. Other immediate post-treatment observations may include licking the face, shaking the head and squinting. These effects should disappear within several minutes following exposure without requiring treatment. Individual sensitivities while rare, may occur after using any pesticide product. If signs of sensitivity occur, consult a veterinarian immediately. Certain medications can interact with pesticides.
Activyl has been tested in cats to make sure it is not easily rinsed or washed off. It is quick drying and it remains effective after shampooing and swimming. Bathing your pet is not required prior to applying Activyl however your pet should not be allowed to swim or be shampooed within 48 hours after treatment.
Activyl contains indoxacarb, an agent designed as a pro-insecticide. It kills adult fleas and breaks the flea life cycle. This flea treatment is a once-a-month topical for cats and kittens 8 weeks of age or older.
Potential flea hosts were observed in the immediate outdoor premises of the homes of pet owners in both treatment groups. Pet owners in the indoxacarb treatment group said they had seen opossums (77.8%; 14/18), raccoons (61.1%; 11/18) or feral cats (100.0%; 18/18) in their yards. The fipronil (s)-methoprene treatment group was similar with 94.7% (18/19) of pet owners indicating they had seen opossums (68.4%; 13/19), raccoons (36.8%; 7/19) or feral cats (89.5%; 17/19) in their yards.
Geometric mean and percent control of fleas recovered in premises flea traps in naturally infested homes when dogs and cats were treated with indoxacarb or fipronil (s)-methoprene based topical spot-on formulations
The difference in efficacy between the two formulations in this study was further demonstrated when looking at the percent of pets that had no fleas at the end of the study. Of the pets treated with indoxacarb, 77.1% were flea free by the end of the 2 month study, whereas only 15.6% of the pets in the fipronil (s)-methoprene treatment group were flea free by the end of the study.
It is notable that in both treatment groups in the current study there were dogs whose flea infestation levels met or exceeded our maximum pet area count of 250 fleas. Previous studies have indicated that flea infestation levels above 50 in a specific region cannot be reliably counted. Based on the area count methodology employed (23.5% of the total pet flea burden) and previous investigations conducted by these authors, those pets where all 5 body areas examined met or exceeded 50 fleas are actually infested with over 1,000 fleas.
These studies over several years document that it should be expected to see fleas on some treated pets for 2 to 3 months following treatment. This is particularly evident in areas with naturally high levels of flea infestations. Data on the percent of flea free pets post-treatment in a multicentric study conducted in Europe are similarly informative. In that study, data from Spain, a country with a high initial flea infestation rate, demonstrated that 70.3-72.7% of dogs and cats were flea infested on day 0. Whereas after two monthly applications of fipronil (s)-methoprene, 33.3%-34.6% of dogs and cats, still had fleas.
The intermittent-light flea traps used in these in-home investigations provide an estimate of development and flea emergence in a home. Following two monthly applications of indoxacarb or fipronil (s)-methoprene topical spot-on formulations to the pets, premises flea counts were reduced by 97.7% and 84.6% respectively. A previous laboratory study demonstrated that a single topical spot-on treatment of indoxacarb to cats eliminated or dramatically reduced egg production and reduced the viability of the few eggs that were produced for up to 6 weeks after treatment. Given the effect of indoxacarb on adult fleas, flea egg production and egg viability, the 97.7% reduction in emerging flea populations observed in this in-home investigation indicates that indoxacarb greatly reduced viable flea reproduction under these tough field conditions.
Cautions: Do not use Activyl Tick Plus on cats, or allow your cat to lick or groom a dog treated with Activyl Tick Plus. Do not use on dogs or puppies under 8 weeks of age or under 4 lbs. Certain medications may interact with pesticides. If signs of sensitivity occur, contact your veterinarian immediately.
We categorized our search by orals/chews, topicals, collars, sprays, and shampoos. We dismissed sprays and shampoos because they offer protection for only days or a week at a time, and pet owners are more likely to misuse them compared with other products. That left us with eight brands of chews, topicals, and collars for cats or dogs. We selected the four brands that were highly recommended by our experts, that kill and protect against a wide range of pests, and that are sold across retailers at a variety of budgets.
To ensure the best outcome for flea and tick treatments, never buy medication without first consulting your veterinarian. Avoid counterfeits by buying products from your vet or a reputable retailer (we like Chewy). Follow the application instructions. Never split doses among pets. If you use a topical, keep pets separated until it dries, to avoid ingestion. And never use dog products on cats because the dosage levels can be dangerous.
1 Dryden MW, et al: Evaluation of indoxacarb and fipronil (s)-methoprene topical spot-on formulations to control flea populations in naturally infested dogs and cats in private residences in Tampa, FL. USA. Parasites & Vectors 2013, 6:366.
Activyl Spot-On for Cats and Kittens is an excellent, once-a-month topical flea treatment for cats and kittens. It contains indoxacarb as its active ingredient which works by bioactivation wherein the enzymes inside the flea stimulate the active ingredient and release its full killing power. This product effectively disrupts the fleas' life cycle and prevents new fleas from reaching adulthood - getting rid of existing fleas and preventing flea infestation. Its fast-acting formula starts killing within 8 hours of application and with continuous use, will provide long-lasting protection for your pets. It features a quick-drying, waterproof formula so the effectiveness will not be affected even after bathing and shampooing. It has no fragrance added and will also remain effective after exposure to sunlight. Available in 3 packs of see-through applicator.
To prevent harm to you and your cat, read entire label and directions before each use. Follow all directions and precautionary statements carefully. For external use on cats and kittens only. Do not use on cats under 8 weeks of age. Do not apply to cats and kittens weighing less than 2 lb.
Choosing safe and effective flea prevention for cats can be tricky. Decades ago, options for killing fleas were limited and toxic. Today, many safe and effective flea control products are available by prescription or over the counter (OTC).
Cats that go outside are more likely to pick up fleas, but even indoor cats can get them from the family dog or when they go to the veterinarian or a boarding facility. Fleas can even hitchhike indoors on your clothes or shoes. If your cat has fleas, you want to get rid of them quickly. A severe flea infestation can seriously damage a cat's skin, induce an allergic reaction, or cause anemia from blood loss. Fleas can also spread parasites like tapeworms and may transmit diseases.
For this guide to the best flea prevention for cats, we conducted research using the quick product reference guide published by the independent, nonprofit Companion Animal Parasite Council and consulted four veterinarians.
A word of caution: Before choosing flea medicine for your cat, talk to your veterinarian. They can advise you on what might be best depending on your cat's temperament, lifestyle, and what parasites they're most at risk for contracting in your area. Read product labels very carefully. No matter what product you choose, never use one labeled for dogs. A product for dogs can make cats extremely sick, and in some cases, it can be fatal.
Revolution Plus Topical Solution is hands down the most complete parasite preventive for cats. It kills adult fleas before they can lay eggs and prevents heartworms. It also treats and controls ear mites, roundworms, hookworms, and black-legged (deer), Gulf Coast, and American dog ticks.
\"The really exciting thing about flea control is there are always new developments in how we can make them better and safer and more effective,\" says Dr. Ashley Bourgeois, a board-certified veterinary dermatologist at Animal Dermatology Clinic. Bourgeois prefers Revolution Plus, saying that its active ingredients (selamectin and sarolaner) are very effective and well-tolerated by cats.
Dr. Keith Harper, a veterinarian at Hayward Veterinary Hospital, also likes Revolution Plus. \"It's one of the most effective topical flea preventions on the market,\" he says. \"I'm a fan of Bravecto as well; it's a longer-lasting flea prevention, effective against fleas and ticks.\" Bravecto contains fluralaner, which is in the same drug class as selamectin and sarolaner; it is also very effective and well-tolerated by